You Are Not Alone
Information for Individuals

Medications Approved for Treatment of OCD

Selective Serotonin Reuptake Inhibitors (SSRIs) directly affect the neurotransmitter serotonin and are generally very effective in helping to reduce the anxiety experienced by an OCD sufferer.  In cases where therapists recommend the use of medication, they typically recommend trying an SSRI medication rather than the more general SRI medication—because the non-selective SRIs affect multiple neurotransmitters.  Most experts recommend trying the SSRI first because there tend to be fewer side effects.

These SSRIs are currently available in the United States:

  • Fluoxetine (brand name Prozac)
  • Fluvoxamine (brand name Luvox)
  • Paroxetine (brand name Paxil)
  • Sertraline (brand name Zoloft)
  • Citalopram (brand name Celexa)
  • Escitalopram (brand name Lexapro)

This Serotonin Reuptake Inhibitor (SRI) is also available:

  • Clomipramine (brand name Anafranil)

These Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) are available:

  • Venlafaxine (brand name Effexor)
  • Duloxetine (brand name Cymbalta)

Medications for OCD do not work immediately.  A person may begin to notice some improvement in three to four weeks, but it may take up to 12 weeks or longer to realize the full benefits of a medication.  While research shows that the SSRIs are more or less equally effective, some people may notice more of a benefit from one medication over another.  A doctor can help you find the right medication that works for your symptoms and your body chemistry.

Medication alone is typically not as effective as Cognitive Behavior Therapy (CBT) in treating OCD.  And sadly, when an OCD sufferer stops taking the medication, the benefits usually also stop.


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